Vestibular platform for head-fixed mice
Overview
This device provides vestibular stimulation for head-fixed experiments in mice. It can be combined with different physiological and behavioural recording modalities. It follows a modular, low-cost and open-source model. This documentation provides the assembly and operation guide for users with some experience in rapid manufacturing, electronics and development boards/microcontrollers (such as Arduino).
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| Figure 1. Global view of the setup and main components |
Features
- fully open source
- low cost
- easy to assemble
- modular design, modules can be added depending on experimental needs
Main components
The main components of the stage are labeled in the figure above. The rotary platform is actuated by a stepper motor using a timing belt. An incremental encoder is coupled with the motor shaft to measure the angular position and a Hall effect sensor is used for homing purposes. Compressed air is used to keep a polystyrene sphere floating without friction inside the sphere holder. The crossed roller bearing holds the rotating and non-rotating parts together. The rotary joint enables multiple electric connections between the rotary platform and the base. The device is intended to be used for behavioural experiments combined with extracellular recording and optogenetics. There are two operating modes: closed-loop and open-loop. In closed-loop, the rotation of the sphere on the vertical (yaw) axis is measured using an optical sensor and is used to generate a motor rotation of an adjustable magnitude in the opposite direction. In open-loop mode, motor rotation is independent of the animal’s movement and can be controlled by the experimenter.